"What we can say with certainty is that all three vaccines provide levels of protection that are comparable to some of the best vaccines we have for other serious infectious diseases for which we routinely vaccinate people," the health officers said.
Concerns about the Johnson & Johnson vaccine stem from its perceived lack of effectiveness in clinical trials.
In phase three clinical trials, which included some 40,000 participants, the J&J vaccine was roughly 66.1% effective at preventing symptoms after four weeks, 85.4% effective at blocking severe cases and 100% effective at preventing deaths and hospitalizations, according to the company.
The two-dose vaccines developed by Moderna and Pfizer/BioNTech showed slightly higher effectiveness at 95%, leading to some concern that the J&J vaccine is undesirable.
The health officers argued, however, that the clinical trial results are not perfect comparisons due to their different trial populations and the different phases of the pandemic in which trials were completed.
The three vaccines have also not been studied head-to-head, the health officials said.
"If this had occurred in the absence of a prior announcement and implementation of 94 and 95% efficacy (vaccines), one would have said this was an absolutely spectacular result," National Institute of Allergy and Infectious Diseases Director Dr. Anthony Fauci said about the J&J vaccine during a media briefing in January.
In addition, the J&J vaccine has several benefits that those from Pfizer and Moderna do not, including much less cumbersome storage requirements and the need for only one dose, eliminating the need to return for a second dose three weeks after the first.
"With COVID-19 continuing to circulate as we work toward community immunity, our collective medical advice is this: the best vaccine is the one you can get the soonest," the health officers said.
Residents in each of the 10 counties are encouraged to contact their medical provider or public health department if they have questions about the vaccines.
Residents can visit https://myturn.ca.gov or call 833-422-4255 to find out if they are eligible for a vaccine or sign up to be notified once it is their turn.
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